NAD+ is a molecule your cells rely on for energy, repair, and staying sharp as you age. Levels naturally decline over time — restoring them is linked to better focus, steadier energy, and healthier aging at the cellular level.
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NAD+ plays a crucial role in cellular energy production, metabolic processes, and signaling pathways. It is central to the production of ATP, the body’s main energy currency, and is vital for sustaining the energy demand of cells. NAD+ is also involved in DNA repair, helping to maintain genomic integrity and cellular longevity.
NAD+ levels decline as we age. Restoring our NAD+ levels can help maintain sirtuin activity, which helps to regulate various cellular processes including gene expression, mitochondrial function, and stress resistance, resulting in healthier aging.
Leveraging NAD+ levels will support energy production by enhancing mitochondrial function, helping the cells to produce more energy, improving metabolic health by supporting the pathways that regulate glucose and lipid metabolism, promoting neuroprotection by reducing oxidative stress and supporting brain function.
As a result, users will experience naturally increased energy levels and healthier aging.
Published in 2018 in Nature Communications, this double-blind, randomized trial in healthy middle-aged and older adults showed that chronic oral nicotinamide riboside (NR, an NAD+ precursor) supplementation was safe, well-tolerated,…
Read Paper →This comprehensive review details how age-related NAD+ decline drives metabolic/neurodegenerative diseases and cancers, while upregulation (e.g., via precursors) prevents this and extends lifespan in model organisms.
Read Paper →This New England Journal of Medicine study showed that weekly retatrutide doses up to 12mg led to an average 24.2% body weight reduction over 48 weeks in adults with obesity,…
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